Everyone knows calamine lotion tends to be a thick, messy cream that's almost not worth the effort. Eliminate the sticky, messy application with Spray Calamine Lotion from up & up™ and you'll get instant relief from itchy, rashy skin with half the time and effort. A mist administers the lotion evenly across the affected areas, to start working everywhere at once. If you've had run-ins with mosquitoes or poisonous plants, this is the spray to use to get back out there faster and with more comfort.