Manage your aches with Equate Extra Strength Headache Relief Caplets. Equate Extra Strength Headache Relief Caplets temporarily relieve minor aches and pains due to a headache, cold, arthritis, toothache, muscular aches, and premenstrual and menstrual cramps. Each of these fast-acting caplets is formulated with 250 milligrams of Acetaminophen, 250 milligrams of Aspirin, a nonsteroidal anti-inflammatory, and 65 milligrams of caffeine to give you the headache relief you need to get back to your day....