All Day Protection. Meclizine Hydrochloride - Antiemetic. The Once-A-Day Travel Tablet. Prevents Motion Sickness. Causes Less Drowsiness. Bonine works up to 4 times longer and causes less drowsiness than original dramamine. Bonine protects travelers against air, sea and car sickness for up to 24 hours. Available in a convenient chewable tablet, Bonine can be taken without liquids - anytime, anywhere.